Human hair plays an important and often underrated role in our lives besides cosmetic functions. Hair keeps the head warm and is considered a cushion for the skull. The physical appearance and cosmetic packaging of our hair also gives people impressions about us, which is why it can be very disheartening to experience hair loss. At some point in the life of a person, most especially women, there is a period that is burdened with cosmetic dramas that utilise hair straightener and this is usually headed by hair loss. Often times than not, the loss of hair is not due to any serious causes, but the inability to maintain our ornamental interface makes it very troubling for most people. And the most common kindof hair loss is the androgenetic alopecia, even though there are a number of other forms.
Whether loss or not, most hair disorders are considered to be hereditary, the implication of this is that they are often unpreventable. When they occur however, hereditary or not, they are often caused by a range of factors that range from inflammatory skin diseases to inflammatory hair follicles. There are several causes of hair loss, the most common ones include inflammatory skin diseases and an inflammation present in the hair follicles. The provocations for these conditions are not exactly known, it is also of considerable bewilderment why only some parts of the scalp or patch are affected and not some others. Inflammation of the scalp is caused by irregular levels of a class of protein called “cytokine” which are secreted by the cells of the immune system. They are excessively produced by immune cells that are overactive and therefore result in an abnormal level. In autoimmune situations, the body’s immune system is designed in a way such that cells and organs are seen as foreign bodies and organisms, this enables the body to put an apparatus in place that allows them to be destroyed. This leads to inflammation which is the body’s natural response to microorganisms. In cases of hair loss however, the body also takes hair follicles as external objects, making it destroy them.
This results into alopecia, it is worthy to note that inflammation also causes malnourishment of the hair roots, due to the fact that it damages the scalp. In some instances, hair follicles are destroyed due to the stem cells’ being affected by inflammation at the upper aspect of the follicle, substituting them with scar tissues instead. Also, in most instances, the damage is measured to be permanent and irreversible, making many believe that hair will not regenerate even after treating the inflammation. Regulatory T (Tregs) cells are types of immune cells that are associated with the control and prevention of inflammation in the hair patch.
They cause stem cells in the scalp to promote healthy growth of hair, without which the follicles will be unable to regenerate and can cause baldness. The logic behind this reasoning is that stem cells allow the growth and repair of worn out tissues in the body, thus Tregs are an essential part of the regrowth of loss hair follicles. Research on this procedure was able to safely infer that the relationship between Tregs and hair growth is a very important one, such that the residence of Tregs in stem cells within hair follicles allow them to regenerate quickly. Besides the regeneration, it also showed that hair patches within which Tregs resides have a kind of resistance to patch inflammation. Allowing the conclusion that Tregs is an anti-inflammatory component that allows healthy hair regrowth to be drawn.